We expect advertisements to be visible. However, you should not let the advertisements distract users or prevent them from consuming the site content. For example, advertisements, supplement contents, or interstitial pages (pages displayed before or after the content you are expecting) that make it difficult to use the website. Learn more about this topic.38
QUOTE: “I think there is probably a misunderstanding that there’s this one site-wide number that Google keeps for all websites and that’s not the case. We look at lots of different factors and there’s not just this one site-wide quality score that we look at. So we try to look at a variety of different signals that come together, some of them are per page, some of them are more per site, but it’s not the case where there’s one number and it comes from these five pages on your website.” John Mueller, Google 2016
The SEO starter guide describes much of what your SEO will do for you. Although you don't need to know this guide well yourself if you're hiring a professional to do the work for you, it is useful to be familiar with these techniques, so that you can be aware if an SEO wants to use a technique that is not recommended or, worse, strongly discouraged.